To successfully navigate chemical gradients, microorganisms need to predict how the ligand concentration changes in space.Due to their limited size, they do not take a spatial derivative over their body length but rather a temporal derivative, comparing the current signal with that in the recent past over the so-called adaptation time.This strategy
Epigenetic alterations in cancer
Genetic and epigenetic modifications in DNA contribute to altered gene expression in aging and cancer.In human cancers, epigenetic NATO straps changes such as DNA methylation, histone modifications, micro RNAs and nucleosome remodelling all control gene expression.The link between the genetics and epigenetics in cancer is further shown by existence
Case report: An occult hepatitis B virus infection reactivation in an HIV/HCV coinfected patient during an immune reconstitution inflammatory syndrome
The natural history of occult hepatitis B virus infection (OBI) and the Potting boxes mechanism involved in HBV reactivation are only partially understood.As regards people living with HIV (PLWH), HBV reactivation is estimated to occur with an incidence ratio of 0.019 cases per 100 person-year.Here we report the case of OBI reactivation in a HIV/HC